MACS Matchmaker
Interactive simulators for the kinetic and equilibrium binding models used in this platform. Each page shows the governing equation, the assumptions behind the model, and lets you explore how parameters shape the observed response.
Langmuir 1:1
Reversible 1:1 interaction between one analyte and one ligand.
4PL Equilibrium (Dose-Response)
Four-parameter logistic curve for steady-state titrations: bottom, top, EC50, and Hill slope.
Heterogeneous Ligand — independent sites
Two independent ligand populations on the same surface, represented as the sum of two Langmuir interactions.
Heterogeneous Analyte — parallel reactions
Interactive parallel-reaction simulator for a stable sample mixture with two effective kinetic components.
Langmuir 1:1 — Partially Non-Dissociative
Sequential cycles where one shared fraction of bound analyte remains on the surface.
Langmuir 1:1 — Non-Dissociative Multi-Relation
Interactive Langmuir 1:1 simulator with an independent non-dissociating fraction for every injection.
Langmuir 1:1 with Mass Transport
Analyte diffuses through a boundary layer before binding, separating transport from intrinsic kinetics.
Langmuir 1:1 — Decaying Surface
The active ligand population decays exponentially during the measurement.